The remaining choices are Ted Cruz, Marco Rubio or John Kasich. Kasich, is seen as a harmless, likeable Republican. Still, he has no huge ground swell and his political stance beyond likability is hard to define. Ted Cruz is openly reviled by apparently anyone who has ever met him besides his wife and children, which could obviously lead to problems in a general election.
If Rubio can secure Florida, he may gain a foothold on which to leap forward and secure the nomination as the only viable establishment candidate.
With the possibility of a brokered convention - a contested convention where no clear candidate has secured the majority of delegates - Cruz and Rubio would be vying for that second spot. Cruz's unpopularity among his colleagues could be his undoing as Rubio steps into the role he has been bred for since his 2012 Republican National Convention speech proclaiming himself the GOP version of Obama.
Though this would not be the "YES WE CAN," victory either the GOP or Rubio envisioned, it would launch him into a position to unify a broken political party and bring a Latino nominee to the forefront. That could help the GOP improve its growing diversity problem thanks to years of implied anti-immigrant and minority sentiment and a campaign season of openly hostile commentary from Donald Trump.