Brexit a buying opportunity for US stocks, Wells Fargo strategist says

There is a lot of confusion surrounding the impact of the Brexit vote, but one thing is clear — investors should take this opportunity to start buying U.S. stocks, strategist Scott Wren said Tuesday.

That's because Britain's vote to leave the European Union is more of a speed bump on the way to improving economic growth, not a brick wall, he explained.

"The domestic economy here in the U.S., the trajectory of that economy and really much of the world, is going to be completely unchanged by the Brexit vote," the senior global equity strategist for Wells Fargo Investment Institute said in an interview with CNBC's "Closing Bell."

In fact, he expects money to flow into the U.S. stock and bond markets because of the vote.

"We have slow growth, but it's dependable. The rest of the world knows that," said Wren.

Therefore, those who have cash on the sidelines should leg into U.S. large-cap stocks with about one-third of it. If the market trades lower, Wren says, he would put the rest of the money to work.

"We want our clients stepping in here; they're certainly sitting on cash like many retail investors are. That's easier said than done, but I think a year from now when you look back, you will have said this is a buying opportunity."

The Dow Jones industrial average closed almost 270 points higher Tuesday after a two-day sell-off following the Brexit vote.

— CNBC's Laura Petti contributed to this report.