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In front of a young crowd at Drexel University, Biden excoriated Trump for two comments in particular from the first presidential debate Monday: one on taxes and the other on the housing burst of 2008.
"He acknowledged that he didn't pay taxes because he said ... because he's smart; makes him smart," Biden said, referring to an interjection Trump made when Clinton suggested he possibly did not pay federal taxes.
"Tell that to the janitor in here who's paying taxes!" answered Biden raising his voice.
"Tell that to your mothers and fathers who are breaking their neck to send you here, they're paying taxes ... It angers me, it angers me," Biden added.
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The former senator from Delaware also criticized comments from Trump suggesting that the housing bubble collapse of 2008 was "good business" for him.
"What in the hell is he talking about?" the vice president wondered aloud to the few hundred gathered at Drexel's "Great Court."
"Can you imagine Ronald Reagan ... saying it's good business to take advantage of people's misery? Rooting for that misery?" he said bitingly.
Biden made an impassioned plea to the young people in the room to get out and vote for Clinton. He acknowledged that while many millennials are not "overjoyed" with Trump or Clinton, President Trump is not an acceptable outcome.
Biden concluded with a defiant optimistic message that the United States was second to no country.
"We own the future, we own the finish line!" He concluded to cheers.