Many analysts also do not expect government support will come at this point, or that it will even be necessary, however. Many also don't see a systemic risk to other banks or that this could trigger a financial crash like that seen in 2008.
"It's not a Lehmans moment in the offing. Banks are generally better capitalized and able to cope with adverse shocks. And Deutsche's derivatives exposure can be overstated," Neil Wilson, a markets analyst at London-based spreadbetter ETX Capital said in a note Wednesday. "Deutsche's problem is not capitalization – it's just that its costs have soared (mainly through litigation and fines) and it's not that profitable anymore."
Meanwhile, Markus Stadlmann, chief investment officer of Lloyds Private Banking, told CNBC Thursday that investors shouldn't throw the "baby out with bath water" with regards to the bank.
"Deutsche still has a very strong franchise, I think John Cryan is a very strong CEO who can turn the ship around," he said. "It has a lot of clout in European markets but also in the Middle East, some Asian markets ... it's more of a balance sheet, liquidity, capital issue."