The 10:30 a.m. ET remarks will be her first since she conceded the contest to Trump early Wednesday. Clinton did not appear at her campaign's election night rally at the Javits Center in Manhattan.
Trump's surprise victory was fueled by apparent wins in the swings states of Florida, North Carolina, Ohio and Pennsylvania. Trump has a projected 278 electoral votes with four states left to be called by NBC.
Trump said he received a call from Clinton shortly before he gave a victory speech early Wednesday in Manhattan.
"She congratulated us, it's about us, on our victory. And I congratulated her and her family on a very, very hard fought campaign," Trump said.
Clinton's event Wednesday starts at 9:30 a.m. but she will not speak until 10:30 a.m., aides said.