Japan's Takeda Pharmaceutical said on Wednesday it had completed enrolment for a 20,000-subject dengue vaccine trial, the largest clinical study in its history, signalling the global ambitions of its vaccine business.
Japan's largest drugmaker has taken a conscious decision to become more international under its French CEO Christophe Weber, who took over in 2015.
The international dengue study will test the experimental vaccine on 20,100 children and adolescents in eight countries in Latin America and Asia where the mosquito-borne disease is endemic. Initial results are expected in 2018.
Dengue kills about 20,000 people per year and infects hundreds of millions, and the virus is becoming much more prevalent and widespread.