The Dow Jones industrial average fell 27.05 points, or 0.13 percent, to close at 20,913.46, with Boeing leading decliners and Apple the top advancer.
The S&P 500 advanced 4.13 points, or 0.17 percent, to end at 2,388.33, with information technology leading five sectors higher and telecommunications lagging.
The Nasdaq gained 44 points, or 0.73 percent, to 6,091.60.
About four stocks advanced for every three decliners at the New York Stock Exchange, with an exchange volume of 753.89 million and a composite volume of 3.193 billion at the close.
—CNBC's Jeff Cox and Reuters contributed to this report.
On tap this week:
Earnings: Apple, Aetna, Archer-Daniels Midland, Merck, Pfizer, CVS Health, BP, MasterCard, Altria, ConocoPhillips, WebMD, Weight Watchers, FireEye , Devon Energy, Etsy, Gilead Sciences, Newfield Exploration, Anadarko Petroleum, Cummins, Coach, Mosaic, Allstate, Becton Dickinson, Eaton, Lumber Liquidators
April vehicle sales
Two-day Fed meeting begins
Earnings: Facebook, Time Warner, Volkswagen, AIG, Kraft Heinz, MetLife, Tesla Motors, Avis Budget, Tableau Software, Pioneer Natural Resources, Yamana Gold, Estee Lauder, Southern Co, Garmin, Sprint, Wellcare Health, Molson Coors Brewing, Humana, Cheesecake Factory, Fitbit, MetLife, Groupon
8:15 a.m. ADP payrolls
9:45 a.m. Services PMI
10:00 a.m. ISM non-manufacturing
2:00 p.m. Fed decision
Earnings: A-B InBev, Occidental Petroleum, Royal Dutch Shell, Adidas, Kellogg, Viacom, Beazer Homes, AMC Networks, Siemens, Dunkin Brands, Chesapeake Energy, Marathon Oil, Allscripts Healthcare, El Pollo Loco, Shake Shack, PerkinElmer, Zynga, Zillow, Wageworks, DeVry Education, CBS, Activision Blizzard, Herbalife
8:30 a.m. Jobless claims
8:30 a.m. Trade deficit
8:30 a.m. Productivity
8:30 a.m. Unit labor costs
10:00 a.m. Factory orders
Earnings: TransCanada, Cognizant Tech, Moody's, Cigna, CenterPoint
8:30 a.m. Nonfarm payrolls
3:00 p.m. Consumer credit
11:30 Fed Vice Chairman Stanley Fischer at Hoover Institution Monetary Policy Conference
12:45 a.m. San Francisco Fed President John Williams
1:30 p.m. Chicago Fed President Charles Evans, Boston Fed President Eric Rosengren, St. Louis Fed President James Bullard on panel at Hoover Institution
1:30 p.m. Fed Chair Janet Yellen in webcast from Brown University at event on 125 Years of Women at Brown