CNBC asked the Secret Service on Tuesday whether it was aware of Shkreli's hair bounty for Clinton, who is entitled to lifetime protection from the Secret Service because she is the spouse of former President Bill Clinton.
Joseph Casey, a spokesman for the Secret Service, said, "As a matter of practice the Secret Service does not comment on the means and methods of protective operations or investigations."
But Shkreli later in the day wrote on Facebook that the Secret Service had reached out to him about the initial post.
He also later amended his initial post to include a disclaimer: "(this is satire, meant for humor and not an endorsement of violence against a truly wonderful public servant)."
Also Tuesday, Shkreli put up for sale his infamous Wu-Tang Clan album.
In the eBay listing, Shkreli wrote:
This is the one and only Wu-Tang album.
I decided to purchase this album as a gift to the Wu-Tang Clan for their tremendous musical output. Instead I received scorn from at least one of their (least-intelligent) members, and the world at large failed to see my purpose of putting a serious value behind music. I will be curious to see if the world values music nearly as much as I have. I have donated to many rock bands and rappers over the years to ensure they can continue to produce their art when few others would.
At any time I may cancel this sale and I may even break this album in frustration. I will donate half of the sale proceeds to medical research. I am not selling to raise cash—my companies and I have record amounts of cash on hand. I hope someone with a bigger heart for music can be found for this one-of-a-kind piece and makes it available for the world to hear.
The New York Post's famed gossip column "Page Six," which broke the news about the auction, reported that Shkreli, when reached by phone Tuesday night, "refused to say where he would donate the money or what he would do with the remaining cash."
"Instead he unleashed a string of expletives and then requested to engage in a lewd act with a reporter," Page Six reported.
In June, shortly before his trial began, Shkreli's high-powered criminal defense lawyer Benjamin Brafman told a federal judge that his client, who claimed to be worth $70 million in 2015, "doesn't have any cash."
Brafman during the same court hearing said that Shkreli's stock in another drug company he had founded, Turing Pharmaceuticals, is worth between $30 million and $50 million.
But the lawyer said Shkreli could not sell off part of that stake to pay his mounting legal bills because Turing is privately held, and any sale of Shkreli's share of the company is subject to agreement by other stakeholders.
Brafman said at the time that the Wu-Tang Clan album is "probably worthless."
And the lawyer said that the "preposterous promises" that Shkreli had recently made to pay $40,000 for a Princeton student who could produce a mathematical proof, and a $100,000 reward for the identity of a murderer of a Democratic National Committee staff, were efforts to win attention from the public.
On Wednesday, when contacted by CNBC, Brafman said he had no comment on the sale of the Wu-Tang Clan album.
Brafman said the Secret Service conducted a "routine inquiry" into Shkreli's Facebook post.
It "was not a serious matter," the lawyer said.