Republican senators faced a major new hurdle Friday in their efforts to overhaul the nation's health-care system when Arizona Sen. John McCain issued a statement that he could not "in good conscience" support the latest measure.
McCain's lack of support left Republicans with no room for further defections from other GOP senators who joined McCain in July in voting down the last attempt to repeal and replace the Affordable Care Act, including Maine Sen. Susan Collins and Alaska Sen. Lisa Murkowski.
The latest Senate bill, which faces a Sept. 30 deadline to win 50 votes, faces strong opposition from Democrats, who have said it will raise the cost of health insurance and leave millions of American families without coverage.