Sage Therapeutics said Thursday its drug to treat moderate and severe postpartum depression met the main goal in two late-stage studies.
The stock soared as much as 50 percent in premarket on Thursday.
The drug, brexanolone, achieved lower rates of depression in patients compared with a placebo in both trials.
Postpartum depression is a common complication of childbirth that affects about 10 to 20 percent of women giving birth in the United States, the company said.
—CNBC's Berkeley Lovelace Jr. contributed to this report.