"Singapore will prohibit all commercially traded goods from, or to, the Democratic People's Republic of Korea (DPRK)," the city-state's customs said in the notice sent to traders and declaring agents last Tuesday, referring to the country by its official name.
The suspension would take effect from Nov. 8, Fauziah A. Sani, head of trade strategy and security for the director-general of customs, said in the notice.
Repeated breach of the new prohibitions is punishable by a fine of up to S$200,000 ($147,340.50) or four times the value of the goods traded, imprisonment of up to three years, or both, it added.
Singapore is North Korea's seventh largest trading partner. The Philippines, Pyongyang's fifth biggest trading partner, suspended trade with North Korea in September to comply with a U.N. resolution.
Tension on the Korean peninsula has escalated as North Korea's young leader, Kim Jong Un, has stepped up the development of weapons in defiance of U.N. sanctions.
North Korea has tested a series of missiles this year, including one that flew over Japan, and conducted its sixth and biggest nuclear test in September.
Pyongyang maintains a diplomatic presence in Singapore, with an embassy in its financial district.