Since Trump took office early last year, deal makers have steadily become accustomed to a more hostile U.S environment.
Headline deals blocked by Washington in recent months included, notably, the $1.2 billion acquisition of Moneygram International by China's Ant Financial in January.
Delays in gaining approval led to the abandonment of a plan for HNA to buy a $200 million stake in Skybridge Capital, a hedge fund founded by Trump's former aide Anthony Scaramucci.
Other scrapped deals have ranged from a $25 million bid for a stake in the Chicago Stock Exchange, which was blocked by the U.S. Securities and Exchange Commission, to a $16.5 million offer for a U.S. pig breeder.
Although, the door is not entirely closed.
This month the U.S. approved the $2.7 billion takeover of U.S. insurer Genworth Financial by China Oceanwide Holdings, a deal first struck in October 2016.
Deal makers remain hopeful that any easing in the current tensions could boost China-U.S. deal volumes once more.
"This may not be the best timing. When the trade war is over, people will come back," said Samson Lo, head of Asia M&A at UBS. "Investors will continue to seek to identify attractive assets in the U.S."
A senior executive with a Hong Kong-based investment firm confirmed he was still looking at U.S. deals.
The new U.S. measures "will definitely impact future deals and curb China's enthusiasm," he said. "but we are still engaged in conversations."
Another executive at the private equity arm of a Chinese state bank said the firm is also still actively studying U.S. deals.
"We are trying to see how we can participate," she said.
"Maybe we will just go for a very small stake."
Still, investments in technology have become a whole front in their own right in what some bankers consider a "cold war" for cross-border deals in the sector.
Reuters reported this week that China has begun downplaying Made in China 2025 — a key policy designed, among other things, to back overseas investment in key sectors, but which had provoked alarm in the West.
"Many of our tech clients understand the prospects. They are all cautious and will not pursue big investments at this point in time," said one senior Hong Kong-based investment banker.
Chinese investors have announced just five U.S. technology company acquisitions so far this year, totalling just $278 million, Thomson Reuters data shows - the lowest figure in five years.
Joseph Gallagher, head of Asia Pacific M&A at Credit Suisse, noted that issues around tech deals were not only a U.S.-China issue as European governments are also wary of China getting hold of key technology.
"Europe is becoming more difficult for Chinese acquisitions as well," he said. " If the tech cold war went away, there would be significant tech M&A activity, but that's not likely to happen."