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Stocks making the biggest moves in the premarket: AstraZeneca, ViacomCBS, SunRun & more

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Wall Street set for a lower open following Monday's gains

Take a look at some of the biggest movers in the premarket:

AstraZeneca (AZN) – The drugmaker's stock fell 2.9% in premarket trading after an independent monitoring board told U.S. health officials that the company may have given incomplete efficacy data from its Covid-19 vaccine trial. The Data Safety Monitoring Board said it wanted AstraZeneca to work with it to review the data to ensure it is accurate and up to date.

ViacomCBS (VIAC) – ViacomCBS will raise $3 billion from stock offerings, following a recent runup in its stock price. The media company will sell $2 billion in class B common shares and $1 billion in mandatory convertible preferred shares. Media companies with streaming services – like the company's recently rebranded Paramount+ — have been ramping up spending on new content. Viacom fell 5.3% in premarket action.

SunRun (RUN) – The solar power company's stock jumped 2.5% in premarket trading after Goldman Sachs upgraded it to "buy" from "neutral," pointing to accelerating growth and valuation. SunRun gained 3.2% Monday after being rated "positive" in new coverage at Susquehanna Financial.

Microsoft (MSFT) – Microsoft is in talks to buy videogame chat community Discord for more than $10 billion, according to people familiar with the matter who spoke to Bloomberg. One person familiar with the matter said Discord is more likely to go public than to sell itself, however.

Boeing (BA) – Boeing struck a deal for a $5.28 billion two-year revolving credit agreement, higher than the $4 billion that the jet maker was originally said to be seeking. Boeing shares fell 1% in the premarket.

Baidu (BIDU) – Baidu made its debut on the Hong Kong stock exchange following a secondary listing that raised $3.1 billion for the China-based internet company. Baidu's U.S. shares sank 2.3% in premarket trading.

Bilibili (BILI) – Bilibili is set to raise $2.6 billion following the pricing of a Hong Kong secondary listing, according to people with direct knowledge of the matter who spoke to Reuters. The price for the online video site operator's stock was said to be 2.6% below its Monday close in U.S. trading.

Tencent Music Entertainment (TME) – Tencent Music reported quarterly results that came in slightly below Wall Street forecasts. The music streaming service also announced a multi-year licensing agreement with Warner Music and the formation of a joint venture music label with Warner in China. Tencent shares dropped 3.2% in premarket trading.

Peloton (PTON) – Peloton recently bought three companies in a flurry of acquisitions, according to a Bloomberg report. The fitness equipment maker's acquisitions involved artificial intelligence, wearables and hardware.

Apollo Global (APO) – The private-equity firm's shares rose 1.4% in premarket action after Citi upgraded the stock to "buy" from "neutral." Citi said Apollo's recent corporate governance moves should reduce headline and other risk factors.

Discovery (DISCA) – Discovery lost 3% in premarket trading after UBS downgraded the media company's stock to "sell" from "neutral," noting the valuation after the stock nearly quadrupled over the past 12 months. UBS said the risk/reward profile is more challenging at current levels.

Pfizer (PFE) – CEO Albert Bourla told The Wall Street Journal that the drugmaker would expand its mRNA vaccine business to target other viruses and pathogens beyond the coronavirus. Bourla said the company gained a decade's worth of experience in working with Germany's BioNTech (BNTX) on the Covid-19 vaccine and is now ready to proceed on its own.