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European stocks close lower as investors assess global data, earnings; Sanofi falls 19%

This is CNBC's live blog covering European markets.

European stocks closed lower on Friday, with earnings and the state of the global economy keeping sentiment on edge.

The benchmark Stoxx 600 ended down 0.8%, with most sectors and major bourses in negative territory. Healthcare stocks slipped 2.9% to lead losses, while chemicals stocks climbed 0.8%.

The pan-European index has had a muted week overall but is heading for its worst monthly performance since Sept. 2022, according to LSEG data.

European markets


Company results have caused big movements in individuals stocks. NatWest plunged as much as 17% near the open, before paring losses and ending the session down 11%. The bank reported third-quarter results that showed a lower net interest margin, while the U.K.'s Financial Conduct Authority said Friday morning it had found "potential regulatory breaches" in its report into a banking account scandal that ousted NatWest CEO Alison Rose.

Earlier in the week, Deutsche Bank gained on a forecast beat as Barclays tumbled after it warned of cost-cutting charges ahead.

Investors also remain focused on central bank messaging on "higher for longer" rates and economic indicators as bond yields remain elevated. U.S. gross domestic product grew by 4.9% in the third quarter, ahead of estimates, sparking stock market jitters.

The European Central Bank on Thursday held interest rates steady after an unprecedented run of 10 hikes. It repeated messaging around rates being at the right levels to bring inflation to target if held for a "sufficiently long duration."

ECB President Christine Lagarde told CNBC in a press conference that the bank had not discussed when the first rate cut may come, and to do so would be "totally premature."

"For the moment we are saying we are steady, we have to hold," Lagarde said.

Asia- Pacific stocks were broadly lower despite mainland China bucking the trend, while U.S. stocks were mixed.

European stocks close lower

The pan-European Stoxx 600 index closed 0.8% lower on Friday as investors assessed a fresh batch of corporate earnings.

Healthcare stocks led the losses, down 2.9%, with French drugmaker Sanofi tumbling 19%.

— Sam Meredith

Stocks on the move: Siemens Energy up 9%; Sanofi falls 17%

German power engineering company Siemens Energy rose 9% on Friday afternoon, paring recent losses after the stock price tumbled 35% in the previous session.

German Chancellor Olaf Scholz called the firm "very important," Reuters reported, after it emerged Thursday that the company had sought guarantees from the government.

At the other end of the European benchmark, shares of French drugmaker Sanofi fell more than 17%. The company announced Friday that it had dropped its 2025 profit guidance and said it was reviewing possible separation scenarios.

— Sam Meredith

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Vincent Chaigneau of Generali Investments discusses earnings season and the outlook for stock markets and investing.

Bond rout ‘tremendously dangerous’ for equities, CIO says

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David Neuhauser, CIO at Livermore Partners, discusses risks to the U.S. economy and the threat to equities from bond yields.

Shares of Sanofi tumble 15% after drugmaker abandons 2025 profit target

Shares of French drugmaker Sanofi fell more than 15% on Friday morning shortly after the company dropped its 2025 profit target and announced it was reviewing possible separation scenarios.

The Paris-listed stock, which dropped to the bottom of the pan-European Stoxx 600 on the news, is currently on track for its worst day in 29 years, Reuters reported.

"The intended separation will seek to create two entities, each better equipped to pursue its own business strategy, resourcing and capital allocation and enabling each to focus on long-term growth in its respective markets," Sanofi said in a statement.

Sanofi said the timing of the separation would not happen before the final quarter of 2024 at the earliest and added that the listing would be designed "to drive growth and shareholder value."

— Sam Meredith

CNBC Pro: Worried about a slowdown? One asset management firm shares a way to hedge — and names 10 global stocks

High-yielding stocks have been doing well despite rising interest rates, according to AllianceBernstein.

The asset management firm said it's "premature" to call a peak in rates or bond yields, adding that it expects rates to stay "high and stable" in the short term, and noted that European high equity yield has done well in "similar scenarios."

Subscribers can read more here.

— Amala Balakrishner

Europe stocks to open slightly higher

European markets are seen opening cautiously higher, according to IG data.

The FTSE 100 was last seen opening 12.5 points higher at 7,369, with Germany's DAX and France's CAC 40 flat. Italy's MIB was seen up 25 points at 27,476.

— Jenni Reid

CNBC Pro: ‘An iPhone moment’: Bernstein names global stocks to play the ‘rapid growth’ in battery tech

The energy transition will require more and better batteries, according to Bernstein.

"To enable the energy transition, we will need batteries with higher energy density, faster charging times, and enhanced safety," analysts wrote in an October report.

Lithium-ion battery technology has remained "essentially unchanged" in the past 30 years — and there's a limit to how much more that tech can improve — but that's about to change, the firm said.

Subscribers can read more here.

— Weizhen Tan

The major averages are on pace for three straight losing months

Stocks are limping through the fall, and all three of the major averages are poised to post their third consecutive month of declines.

In October, the S&P 500 is down 3.52%. The Nasdaq Composite is off 4.72%, and the Dow Jones Industrial Average is down 2.16%.

If the month ends with losses for the indexes, it'll be the first time the Dow and the S&P 500 have had three straight months of declines since March 2020.

The last time the Nasdaq fell for three consecutive months was back in June 2022.

-Darla Mercado, Chris Hayes