Japan's Nikkei 225 led gains in Asia as markets in the region rose across the board, following Wall Street's continued rally for a second straight day.
The Japanese benchmark jumped 2.42% to 38,460.08, while the broad based Topix was up 1.67% and ended at 2,710.73.
First-quarter inflation figures from Australia on Wednesday showed the consumer price index rose 3.6% year-over-year, slightly above a Reuters poll expectation of a 3.5% rise. Still, that marked its fifth straight quarter of slowing inflation.
The S&P/ASX 200 pared earlier gains, ending just below the flatline at 7,683 after the CPI reading.
South Korea's Kospi climbed 2.01% and closed at 2,675.75, powered by a 4.11% gain in heavyweight Samsung Electronics, while the small cap Kosdaq was 1.99% higher at 862.23.
Hong Kong's Hang Seng index rose 2.08%, while the Hang Seng Tech index gained 3.5%. Shares of Sensetime soared 31.2% before trading was halted at 11:15 a.m.
China's CSI 300 was 0.44% higher to close at 3,521.62.
Overnight in the U.S., all three major indexes climbed for a second straight session on Tuesday as a strong batch of corporate earnings assuaged concerns over higher rates.
The Dow Jones Industrial Average climbed 0.69%, to mark a four day winning streak. The S&P 500 gained 1.2%, while the Nasdaq Composite saw the largest gain of 1.59%.
— CNBC's Brian Evans and Sarah Min contributed to this report.