Take a look at some of Wednesday's midday movers:
Fastenal was the worst performer on the S&P 500 after an analyst suggested recent company sales data were indicative of a weaker manufacturing economy.
Monsanto traded lower after its Chief Technology Officer Robb Fraley said sabotage is being considered as a possible cause of the finding of unapproved genetically modified wheat in a field in Oregon. Monsanto also said that testing reaffirms that the finding was an isolated incident.
Juniper Networks rose on CEO comments made at a technology conference that the company's routing performance was above average so far in its second quarter. Competitors Cisco Systems and F5 Networks moved higher as well.
Helmerich & Payne traded higher after the company increased its quarterly dividend to 50 cents a share from 15 cents per share.
Red Hat, the company that provides open-source software solutions, was the only S&P 500 stock to hit a 52-week low on Wednesday.
Bed, Bath & Beyond was higher following an upgrade to "buy" from "neutral" at Nomura with a price target of $82 a share.
CareFusion and Micron Technology were the only two stocks to hit a 52-week high on the S&P 500. CareFusion, a global medical technology company also hit an all-time high.
IBM, McDonald's and Walt Disney were the biggest losers on the Dow.
—By CNBC's Lori Spechler
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