Watch CNBC's full interview with Duquesne Family Office CEO Stanley Druckenmiller

Stanley Druckenmiller, Duquesne Family Office chairman and CEO, joins 'Squawk Box' to discuss the state of the U.S. economy, Treasury Secretary Janet Yellen's 'big blunder' of not issuing more long-dated Treasurys when interest rates were low, government spending and the impact on the national debt, market outlook, the Fed's inflation fight, and more.