"You're not a Ghost Killah, I'm sorry," Shkreli sneers while cradling what appears to be a glass of wine.
"You think it's OK to beef with me. But that's' a big mistake ... you're an old man who has lost his relevance," Shkreli said, noting that he was using the rapper's "government name" of Dennis Coles to make his point.
Shkreli then cited the fact that he had, by virtue of forking over $2 million, the one-and-only copy of a Wu-Tang Clan album, entitled "Once Upon a Time in Shaolin."
"If you ever say some dumb s--- again, this album, this 'Shaolin,' I'm going to erase all your s--- from this album, you understand? ... I'm going to erase you from the record book of rap."
"Without me, you're nothing," Shkreli said. "So don't ever mention my name again, or there'll be more of a price to pay than this video."
'Every though I pity you, I have to give you some punishment ... I expect you to write me a written apology, from the heart," Shkreli said. "You think you're the only tough guy from New York City?"
Representatives for Coles were not immediately available to comment.