The Maryland Democrat said on "Squawk Box" he looks forward to either candidate getting the Republican presidential nomination.
"Trump or Senator Cruz will be opponents that we will be able to take on very effectively," said Hoyer, the second-most powerful Democrat in the House. "Trump is a lot rhetoric, but no solutions and simply conclusions."
While making the case for Hillary Clinton as the Democratic nominee over Vermont Sen. Bernie Sanders, Hoyer said voters can see they both have vision. "But what they also see in Hillary Clinton is strategy and policies to realize a vision."
"She's tough. She's focused. She's able," Hoyer said. She's "savvy enough to work with the political structure in Washington, D.C., to get things done."