Elsewhere, Hong Kong's Hang Seng index was up 0.66 percent at 28,358.54 in afternoon trade, with shares of Chinese electric vehicle maker BYD gaining nearly 8 percent.
Singapore's Straits Times index fell 0.37 percent, while India's Nifty 50 was up 0.58 percent.
Singapore-listed shares of SIA Engineering fell 6.07 percent in afternoon trade after reports said JPMorgan was offering a block trade of SIA Engineering shares. The Singapore Exchange filed a query with the company about the share price move.
Australian stocks slipped, with the benchmark ASX 200 falling 49.34 points, or 0.87 percent, to 5,652.1.The energy subindex was down 1.09 percent and the heavily-weighted financial sector fell 0.71 percent.
Major Australian banking stocks were mostly lower, with ANZ shares shedding 2.11 percent, Westpac off 0.87 percent and the National Australia Bank lower by 1.21 percent. Commonwealth Bank shares bucked the downtrend and rose 0.32 percent.
Markets in China and South Korea remain closed for public holidays.
Meanwhile, the Reserve Bank of India's (RBI) monetary policy decision was due on Wednesday. Many analysts expect the central bank to stay on hold, keeping the repo rate at 6 percent.
A Reuters poll found that many economists said the central bank may downgrade its growth forecast following the implementation of the new goods and services tax in the country.
"There is pressure on the committee to ease rates, given that the repo rate is at 6 percent versus below 4 percent CPI inflation," said Radhika Rao, an economist at Singapore-based DBS Bank, in a note. "The RBI is, however, unlikely to react this week as besides a gradual rise in inflation, significant changes in the macro backdrop also need to be assessed further."