Bolton, former U.N. ambassador, has said the U.S. should act pre-emptively against Iran and North Korea because of their nuclear programs. Bolton is expected to encourage Trump to exit the nuclear agreement with Iran and attempt to reinstate sanctions on the country.
Trump on Monday said he was meeting with military advisers to determine who was responsible— Syria's government, Iran, Russia, or all three.
"Trump was obviously calling out [Russia President Vladimir] Putin and Iran, so it's good timing on Bolton's part," said John Kilduff of Again Capital. Bolton's first day on the job was Monday.
"We will see right away how forward leading he's going to be. This could be a sign of things to come," said Kilduff.
The war in Yemen is viewed as a proxy war between Saudi Arabia and Iran, which backs the Houthi rebels. In recent weeks, there have been missile strikes from Yemen, including several aimed at Riyadh. On a recent weekend, seven missiles were interecepted by Saudi Arabia.
Saudi Crown Prince Mohammed Bin Salman led the kingdom into the regional war after the Houthi rebels forced Yemen's president Abd Rabbu Mansour Hadi into exile. The crown prince has been away for several weeks, visiting the U.S. and now France.
There was speculation the prince would order a retaliation for the missile attacks once he returns. Kilduff said Israel could also become more aggressive against activity in Syria.
"This is part of their beef. They don't want Iran on their doorstep. It's a a preview of the growing worries of what could happen with this Israeli-Saudi alliance that has emerged," he said.
Kilduff said the U.S. response to Syria could temporarily send oil several dollars higher, but in the unlikely event it expands beyond Syria it could be worth another $10 or more.
"The interesting question is what happens in Syria? Does what happens in Syria stay in Syria. With the strikes that happened on Sunday, are we going to see Israel become more confrontational? The question is contagion," said Croft. "Will it stay within Syria or will it spill outside the border. Yemen is already spilling outside the border, with the attacks on Saudi Arabia. You get a fear factor, and the fact that we have these two raging proxy wars in the Middle East, and oil doesn't move on it."