Check out the companies making headlines in midday trading:
Bank of America — Shares of Bank of America rose 1.5% after reporting third-quarter profit and revenue that beat analysts' estimates. The bank's consumer and advisory business offset weakness in its trading business. Consumer banking revenue rose 3% to $9.7 billion and the Wall Street trading division revenue fell 2% to $3.88 billion.
McKesson Corp., AmerisourceBergen, Cardinal Health — Shares of three major drug distributors jumped following a Wall Street Journal report that state and local officials could potentially reach a settlement with the companies. The three companies would collectively pay the $18 billion over 18 years as part of the deal. Shares of McKesson rose 4.8%, AmerisourceBergen jumped 3.4% and Cardinal Health rose 2.4%.
Progressive — Shares of Progressive fell 2.8% after the insurance company missed estimates on its third-quarter revenue. Progressive reported revenue of $9.621 billion, lower than the $9.646 billion expected on Wall Street, according to Refinitiv.
Achillion Pharmaceuticals — Shares of Achillion soared 72% on news that the pharmaceutical company will be acquired by Alexion Pharmaceuticals for an initial $930 million or $6.30 per share.
Adobe — Shares of Adobe were pressured by a downgrade to neutral from buy from Citi. The firm said it has concerns the software company can continue the financial momentum of the last five years. The stock fell 2.4%.
Workday — Shares of the software company slid 11.3% following the company's analyst day on Tuesday. Stifel cut its target on the stock to $180 from $210, saying the "premium valuation" causes the firm to "remain on the sidelines." Analysts at RBC also lowered their target to $212 from $225.
U.S. Bancorp — Shares of U.S. Bancorp rose 1.5% after the regional bank beat on the top and bottom lines of its third-quarter earnings. The firm reported earnings per share of $1.15 on revenue of $5.920 billion. Wall Street forecast earnings per share of $1.11 on revenue of $5.815, according to Refinitiv.
Bank of New York Mellon — Bank of New York Mellon shares rose as much as 1.5% and closed up 0.2% after it reported quarterly profit of $1.07 per share, beating the consensus estimate of 99 cents a share. Revenue came in lower than forecasts, as net interest revenue fell 18% from a year ago.
Interactive Brokers — Shares of retail broker Interactive Brokers fell 2.8% after missing on quarterly profit and revenue, in its first earnings report since dropping commission fees. The electronic broker missed estimates by 4 cents a share, with quarterly earnings of 45 cents per share. Revenue also fell short of estimates.
United Airlines — United Airlines rose 2% in midday trading after it raised its earnings forecast for 2019 as travel demand lifts its bottom line. CEO Oscar Munoz said in a release on Tuesday that the airline's third-quarter performance puts it "ahead of pace" after topping estimates for the three months ended Sept. 30.
Tech Data Corp. — Shares of Tech Data surged 11.7% following reports from Reuters that the information technology equipment distributor has been approached by private-equity firm Apollo Global about a possible buyout.
—CNBC's Pippa Stevens and Tom Franck contributed reporting.