UPS, FedEx prepare to distribute Covid vaccines; France extends lockdown until January

The coverage on this live blog has ended — for up-to-the-minute coverage on the coronavirus, visit CNBC's latest live blog.

A staggering number of Americans are dying from the coronavirus each day, as the virus tears through cities and strains the health system. The U.S. recorded 3,124 new Covid-19 deaths on Wednesday, the deadliest single-day tally of the pandemic so far, according to a CNBC analysis of Johns Hopkins University data. The country reported more than 221,000 new Covid-19 infections on Wednesday, and more than 106,000 Americans are currently hospitalized with the virus. The country's top health experts have warned those numbers are only going to climb, as a Thanksgiving-related spike in cases runs into the winter holidays.

The following data was compiled by Johns Hopkins University:

  • Global cases: More than 69.59 million 
  • Global deaths: At least 1.58 million
  • U.S. cases: More than 15.61 million
  • U.S. deaths: At least 292,141