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Patricof, founder of venture capital giant Greycroft, was responding to news that a bipartisan coalition of state attorneys general will investigate Facebook for possible antitrust violations. A separate probe into Google will reportedly be announced next week.
"I don't believe Facebook, Google, or anyone else who will be brought into this have started out to be deliberately monopolistic or cause problems," Patricof said on "Squawk on the Street." "They've had an inexorable growth beyond anyone's original expectations and as a result, they've become too big and too pervasive in our whole lives."
The antirust investigation will focus "on Facebook's dominance in the industry and the potential anticompetitive conduct stemming from that dominance," New York Attorney General Letitia James said in a statement.
"We will use every investigative tool at our disposal to determine whether Facebook's actions may have endangered consumer data, reduced the quality of consumers' choices, or increased the price of advertising," she said.
Patricof said the investigations are "constructive" and suggested the "cost of advertising has been disrupted because everyone is dependent on Facebook or Google as a platform in order to launch something and that's scary."
But, at the same time, Patricof said the investigations may run into challenges because of the nature of the nation's antitrust laws. He said they are outdated and difficult to apply to today's tech titans, since the companies' influence does not necessarily hurt consumers by creating higher prices.
In fact, he said it might be the opposite.
"The old monopoly theory was that monopolies cause prices to go up," Patricof said, but companies like Facebook, Google and Amazon "haven't caused prices to go up as much as they've caused prices to go down."
The nation's first antitrust laws came about in the late 19th and early 20th centuries in response to consolidation in the oil and railroad industries.
Patricof said antitrust laws need to be revised, joining calls from scholars and academics who have argued for a paradigm shift in how monopolies are regulated.
"They need to have new rules and out of it will set the basis" for the next 100 years of antitrust regulation, Patricof said.
The antitrust investigation into Facebook announced Friday is the latest piece of scrutiny in 2019 directed toward large tech companies, which have faced criticism over user data security and consolidation in e-commerce.
The Federal Trade Commission opened an antitrust investigation into Facebook in June, and earlier this year, Democratic presidential candidate Sen. Elizabeth Warren of Massachusetts called for Amazon and Facebook to be broken up by government regulators.
"To me breaking up is one of the easiest alternatives to regulation," said Patricof, who has long donated money to support Democratic politicians.
Patricof said the better solution is putting in place laws that would allow for the democratization of online user data.
The amount of data available to Facebook and Google, which only increases each time the companies acquire smaller competitors, puts them in an unfair position, Patricof said.
But making the data accessible "to outsiders on some equal footing" would limit the power of the largest tech companies, he said.
"It's the data that's the critical aspect and if there is a way to accomplish that through these investigations, I think that's for the good," Patricof said.
Facebook and Google did not immediately respond to a request for comment on Patricof's remarks.